BeFisetin® Fisetin
Be The Golden Standard of Fisetin
· Fisetin is naturally present in many plants, fuits and vegetables in trace amounts, including phyllanthus emblica, strawberries, apples, persimmon, and mulberry fruits and leaves etc.
· Strawberries are a known fruit source that contains the highest amount of Fisetin. 625 gram of Strawberries can provide us 100mg Fisetin.
· BeFisetin is the first SA-GRAS approved Fisetin ingredients. And we are in the process of registering cosmetic raw materials.
Product Brief
Fisetin is getting a lot of attention because of its senolytic properties according to the research. A senolytic is a class of small molecules that are able to induce death of senescent cells and promote human health.
Mechanism and Scientific Research of Fisetin:
· Promote the Apoptosis of Senescent Cells in Dermal
· Reduce SASP and Skin Chronic Inflammation
· Promote Collagen Synthesis in Skin
Scientific Researches
Skin Rejuvenation
Fisetin effectively selectively eliminates senescent dermal fibroblasts with a clearance rate of 66% and inhibits the secretion of SASP, thereby improving skin condition and slowing down the aging process. Additionally, fisetin was found to increase collagen density by 41.2%, contributing to skin rejuvenation.
Biogerontology, 25(1), 161-175.
Improve Skin Inflammation
Psoriasis is a chronic autoimmune skin disease, and fisetin effectively treats its symptoms by inhibiting the Akt/mTOR pathway, promoting keratinocyte differentiation, and enhancing autophagy.
Topical fisetin outperforms rapamycin in improving clinical signs like erythema, scaling, swelling, and epidermal thickness, while histologically reducing epidermal thickness, immune cell infiltration, and rete ridges more effectively.
Frontiers in immunology, 13, 1075804.
Why Choose
BeFisetin
Affirmed GRAS & 100% Botanical
· BeFisetin stands as the premier Fisetin ingredient with Self-Affirmed GRAS status.
· We perform C14 testing to guarantee that BeFisetin is composed of 100% Biobased Carbon, signifying that its origin is wholly derived from plants.
· There is a prevalence of synthetic Fisetin in the market, which is erroneously purported to be natural Fisetin.
Ultra Pure and Safe
· Anacardiaceae plants are the main source of plant lacquer. Many low-quality fisetin products in the market have lacquer impurities.
· BeFisetin has removed all black impurities, reaching a high standard: Botanical flavones ≥ 99%, Fisetin ≥ 98%, and Total impurities ＜ 1%.
· BeFisetin is free of Oil Paint and Wax, ensuring its safety.
Tested with Top Reference Standard (RS)
· Many Fisetin Products on the market are labeled as 98%, yet the actual Fisetin content remains uncertain as the Purity testing is often deceptive.
· A reliable RS sample serves as an unbiased judge and plays a crucial role in ensuring the accuracy of assay testing.
· BeFisetin is examined by a reputable RS, thereby guaranteeing its accuracy and authenticity.
Sustainable and Eco-friendly
· We possess an exclusive Cotinus coggygria planting base, guaranteeing a stable supply and promoting sustainability.
· BeFisetin is produced through a continuous countercurrent extraction line, conserving energy and solvent while minimizing waste.
· BeFisetin is extracted using clean water, without the application of harmful chemicals such as methanol.
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Disclaimer *
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. All information is provided solely for business-to-business customers with the aim of imparting general knowledge and is not intended for end-use consumers.
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