About

Bonerge is an innovative manufacturer that provides comprehensive turn-key solutions within the fields of the Nutraceutical and Cosmeceutical ingredients industries.

Our core focus lies in the discovery and development of ingredients for Ageless Energy, Healthspan and Longevity.

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About

Bonerge is an innovative manufacturer that provides comprehensive turn-key solutions within the fields of the Nutraceutical and Cosmeceutical ingredients industries.

Our core focus lies in the discovery and development of ingredients for Ageless Energy, Healthspan and Longevity.

Contact
About

Bonerge is an innovative manufacturer that provides comprehensive turn-key solutions within the fields of the Nutraceutical and Cosmeceutical ingredients industries.

Our core focus lies in the discovery and development of ingredients for Ageless Energy, Healthspan and Longevity.

Contact
Bonerge

Oil Soluble Pro-Xylane

Utilizing patented emulsification technology, this oil-based Pro-Xylane solution offers a clean, transparent, and stable matrix with a content exceeding 10%, ideal for advanced skincare formulations.

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Bonerge

Water Soluble Fisetin

Fully soluble in water, this clear and transparent Fisetin solution contains 5%–10% active ingredient with customizable concentration options for versatile product applications.

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Bonerge

Urolithin A High-Bioavailability Softgel

Featuring a uniform and easily dispersible core matrix, this softgel formulation enhances the bioavailability of Urolithin A by 5 times, offering optimized efficacy and user experience.

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Fisetin Benefits for Ovarian Health: Supporting POI, PCOS and Menopause

Fisetin Benefits for Ovarian Health: Supporting POI, PCOS and Menopause

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Fisetin Benefits for Ovarian Health: Supporting POI, PCOS and Menopause

Fisetin Benefits for Ovarian Health: Supporting POI, PCOS and Menopause

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Fisetin Benefits for Ovarian Health: Supporting POI, PCOS and Menopause

Fisetin Benefits for Ovarian Health: Supporting POI, PCOS and Menopause

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At Bonerge, we believe that meaningful progress is born from collaboration. We are committed to building open, trusting, and long-term partnerships that drive innovation and create shared value.

At Bonerge, we believe that meaningful progress is born from collaboration. We are committed to building open, trusting, and long-term partnerships that drive innovation and create shared value.

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At Bonerge, we believe that meaningful progress is born from collaboration. We are committed to building open, trusting, and long-term partnerships that drive innovation and create shared value.

At Bonerge, we believe that meaningful progress is born from collaboration. We are committed to building open, trusting, and long-term partnerships that drive innovation and create shared value.

Talk to Our Team
100% Natural Fermented  L-Ergothioneine
100% Natural Fermented  L-Ergothioneine

100% Natural Fermented
L-Ergothioneine

What is QinMito® ?

Powered by a 100% natural fermentation process and exceptional purity, MitoSober elevates L-Ergothioneine to a new standard of excellence and trust.

What is QinMito® ?
100% Natural Fermentation Process

100% Natural Fermentation Process

Produced through a 100% natural yeast fermentation process.

Patented Production Technology

Patented Production Technology

Including patents covering an EgtD enzyme mutant and a sulfoxide synthase used in L-ergothioneine production.

Exceptional Purity

Exceptional Purity

HPLC-tested purity of QinMito L-ergothioneine exceeds 99.99%.

Patented Technology Upgrade Platform

Patented Technology Upgrade Platform

High loading capacity, excellent stability (no phase separation), and clear transparency.

About L-Ergothioneine
Benefits
Clinical Summary
Application
Why Choose
Quality Assurance
Q & A
Recommend Products
About L-Ergothioneine

About L-Ergothioneine

L-Ergothioneine is a naturally rare sulfur-containing amino acid derivative that humans cannot synthesize and must obtain from the diet, with mushrooms as the primary source. The highest EGT levels are found in Pleurotus citrinopileatus (Golden Oyster), followed by wild Boletus edulis.

As a rising star in the healthy aging field, L-Ergothioneine is regarded as a “fifth-generation antioxidant.” Its superior antioxidant efficacy is attributed to its exclusive human transporter, OCTN1—proposed to be renamed ETT (Ergothioneine Transporter).

About L-Ergothioneine

Health Benefits

Telomere Protection & Maintenance

Telomere Protection & Maintenance

Telomere attrition is one of the 14 hallmarks of aging and is strongly linked to age-related diseases. Oxidative stress is a key driver of telomere shortening, while antioxidants help mitigate this damage.

Under oxidative conditions, 8-week ergothioneine supplementation increased median and 20th-percentile telomere length, reduced short telomeres (<3 kb), and slowed telomere loss, highlighting its potential to support telomere health.

J Diet Suppl. 2022;19(2):212-225.

Multi-Organ Targeted Anti-Aging

Multi-Organ Targeted Anti-Aging

Kanazawa University reports that ergothioneine (EGT) shifts survival curves to the right, significantly extending lifespan and delaying frailty. In mice, median lifespan increased by 16% and mean lifespan by 21%.

EGT is efficiently absorbed and transported by OCTN1 to organs such as the liver, kidneys, and brain, giving it multi-organ targeting and broad anti-aging potential.

GeroScience. 2024;46(4):3889-3909

Promotes Neurological Health

Promotes Neurological Health

A double-blind, randomized, placebo-controlled study by the National University of Singapore (NCT03641404) examined the safety and cognitive effects of ergothioneine (EGT) in older adults.

EGT showed no adverse effects on clinical safety markers and improved memory performance with stable neurofilament light levels, suggesting potential to slow cognitive decline.

J Alzheimers Dis. 2024 Dec;102(3):841-854.

Supports Cardiovascular Health

Supports Cardiovascular Health

Health-conscious food patterns (HCFP) are linked to reduced cardiometabolic risk, with ergothioneine (EGT) identified as the strongest positive correlate among 112 metabolites.

Each 1-SD increase in EGT was associated with lower risks of coronary heart disease (−15%), cardiovascular mortality (−21%), and all-cause mortality (−14%), supporting increased plasma EGT via diet or supplementation.

Heart. 2020 May;106(9):691-697.

Telomere Protection &amp; Maintenance

Telomere attrition is one of the 14 hallmarks of aging and is strongly linked to age-related diseases. Oxidative stress is a key driver of telomere shortening, while antioxidants help mitigate this damage.

Under oxidative conditions, 8-week ergothioneine supplementation increased median and 20th-percentile telomere length, reduced short telomeres (<3 kb), and slowed telomere loss, highlighting its potential to support telomere health.

J Diet Suppl. 2022;19(2):212-225.

Multi-Organ Targeted Anti-Aging

Kanazawa University reports that ergothioneine (EGT) shifts survival curves to the right, significantly extending lifespan and delaying frailty. In mice, median lifespan increased by 16% and mean lifespan by 21%.

EGT is efficiently absorbed and transported by OCTN1 to organs such as the liver, kidneys, and brain, giving it multi-organ targeting and broad anti-aging potential.

GeroScience. 2024;46(4):3889-3909

Promotes Neurological Health

A double-blind, randomized, placebo-controlled study by the National University of Singapore (NCT03641404) examined the safety and cognitive effects of ergothioneine (EGT) in older adults.

EGT showed no adverse effects on clinical safety markers and improved memory performance with stable neurofilament light levels, suggesting potential to slow cognitive decline.

J Alzheimers Dis. 2024 Dec;102(3):841-854.

Supports Cardiovascular Health

Health-conscious food patterns (HCFP) are linked to reduced cardiometabolic risk, with ergothioneine (EGT) identified as the strongest positive correlate among 112 metabolites.

Each 1-SD increase in EGT was associated with lower risks of coronary heart disease (−15%), cardiovascular mortality (−21%), and all-cause mortality (−14%), supporting increased plasma EGT via diet or supplementation.

Heart. 2020 May;106(9):691-697.

Clinical Summary

Oral Beauty

Joint Health

Alzheimer

Cardiovascular Health

Oral Beauty

The Impact of QinMito® Supplementation on Skin Health

Enrolled: healthy women aged 40-60 years

Dosage: 500mg QinMito L-Ergothioneine

Control Group: 500mg placebo

Trial Cycle: 56Days

Detection Indicators: Skin heme, Skin inflammation, Trans epidermal water loss, Wrinkle volume, Wrinkle photography, Skin elasticity, Skin firmness, Skin melanin, Skin color. etc.

Result: Compared with the control group, fisetin significantly improved the skin barrier function, skin elasticity and firmness, and reduced the wrinkle area in the subject population.

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Joint Health

Effects of Ergothioneine Supplementation on Joint Mobility and Chronic Pain

Enrolled: 12 adults with mild-moderate complaints of chronic pain affecting range of motion

Dosage: ergothioneine

Control Group: N/A

Trial Cycle: 6 Weeks

Detection Indicators: Rotation through the vertical weight-bearing column (neck, thorax, lumbar, hip, knees) and shoulders, Pain evaluation (questionnaires and Visual Analogues Scales)

Result: Range of motion improvements were seen after ergothioneine-containing supplementation for 1 week, and further improved at 6 weeks. Then, pain reduction for both primary and secondary pain areas remained highly significant after the 6-week wash-out period.

DOI: 10.1016/j.ypmed.2012.02.001

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Alzheimer

The Impact of Ergothioneine Supplementation on Cognitive Decline in Mild Cognitive Impairment

Enrolled: 19 mild cognitive impairment subjects aged 60 or above

Dosage: 25 mg ergothioneine, taken 3 times a week

Control Group: Placebo

Trial Cycle: 1 Year

Detection Indicators: Whole blood profile, Markers of renal and liver functions, Neurocognitive performance, Plasma levels of ergothioneine and its metabolites, Plasma biomarkers related to neurodegeneration

Result: Prolonged intake of ergothioneine showed no toxicity in elderly people. Subjects receiving ergothioneine demonstrated improved performance in assessment of learning ability and stabilized plasma levels of neurofilament light chain, compared with the placebo group.

DOI: 10.1177/13872877241291253

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Cardiovascular Health

The Impact of Ergothioneine Supplementation on Mortality and Cardiovascular Risk

Enrolled: Participants without cardiovascular disease and diabetes mellitus

Trial Cycle: 21.4 Years (median follow-up time)

Detection Indicators: Metabolites associated with the health conscious food pattern (HCFP) were identified using multivariable adjusted linear regressions followed by Bonferroni correction. The healthy dietary biomarkers were subsequently related to risk of cardiometabolic disease and mortality during long-term follow-up with multivariable adjusted Cox proportional hazards models.

Result: Ergothioneine was the metabolite most strongly connected to the HCFP and was associated with a lower risk of coronary disease (↓15%, p=0.01), cardiovascular mortality (↓21%, p=0.002) and overall mortality (↓14%, p=4e-5).

DOI: 10.1136/heartjnl-2019-315485

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Available in

Tablets

Tablets

Hard Capsule

Hard Capsule

Soft Capsule

Soft Capsule

Powders

Powders

Beverages

Beverages

Gummies

Gummies

Liquids

Liquids

Recommended Formulation

StanYouth® CR3
Pro-Xylane
Ectoin
StanYouth® CR3
StanYouth® CR3

StanYouth® CR3

Skin Cell Rejuvenation:
Fisetin clears senescent cells, urolithin A repairs cellular rhythm, and L-Ergothioneine strengthens internal defenses (patent has been applied).

Pro-Xylane
Pro-Xylane

Pro-Xylane

Skin Anti-aging:
L-Ergothioneine can reduce the collagen degradation through MMP-1, while pro-xylane can promote the synthesis of collagen and tight connection of skin, making the skin tougher and more elastic.

Ectoin
Ectoin

Ectoin

Skin Care:
L-Ergothioneine can help skin barrier remodeling by anti-oxidation, and ectoin can enhance the hydration on the phospholipid membrane to improve the ability of withstanding extreme environments.

Quality Assurance

NON-GMO

NON-GMO

ISO 9001

ISO 9001

Gluten Free

Gluten Free

BSE Free

BSE Free

Halal Certified

Halal Certified

Kosher Certified

Kosher Certified

HACCP

HACCP

ISO 22000

ISO 22000

Frequently asked questions

Frequently asked questions

What is the most significant health benefit of QinMito L-Ergothioneine?

L-Ergothioneine is a potent antioxidant with a dedicated transporter protein, OCTN1. This allows for efficient and targeted transport to sites of high oxidative stress such as mitochondria and the cell nucleus, where it precisely scavenges free radicals, resulting in outstanding antioxidant effects.

Is QinMito L-Ergothioneine fermented or synthesized?

QinMito L-Ergothioneine is produced via patented fermentation process.

What is the recommended daily dosage for L-Ergothioneine?

The typical usage dose for L-Ergothioneine in the market usually ranges from 5 to 20 mg per day.

Can the purity of QinMito reach 99.99%?

HPLC purity analysis results for QinMito Ergothioneine can reach 100%.

Does QinMito L-Ergothioneine have Kosher, Halal, or other certifications?

QinMito Ergothioneine is manufactured in a GMP-compliant facility and holds certifications including FSSC 22000, Kosher, and Halal.
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