Platform

Oil Soluble Technology

Technology Platform for Innovation

Harnessing science to advance healthy aging and extend human vitality

Revolutionize Your Formulations with
Advanced Delivery Systems

Unlock the full potential of your active ingredients with our cutting-edge nutrient delivery technologies. Here's
how they give your product a winning edge.

Revolutionize Your Formulations with
Advanced Delivery Systems

Maximize Absorption & Bioavailability

Our nano-scale carriers protect sensitive ingredients from degradation in the digestive system and enhance their solubility, ensuring significantly more active compound is absorbed into the bloodstream and delivered to cell.

Enhance Precision & Cellular Uptake

Their tiny size and engineered surface properties allow for improved penetration of biological barriers and more efficient delivery of nutrients directly to target cells, maximizing their therapeutic effect.

Protect Ingredient Potency & Stability

We encapsulate fragile nutrients, shielding them from oxygen, light, moisture, and pH changes. This guarantees the ingredient remains stable and potent from production until the moment of consumption.

Increase Safety & Reduce Side Effects

Achieve superior efficacy with a lower required dosage. This targeted approach minimizes waste and maximizes tolerability, significantly reducing the potential for adverse effects for a safer consumer experience.

Innovative Technologies And
Product Solutions

Oil Soluble Technology

Water Soluble Technology

High-Bioavailability Softgel

Oil-Soluble Technology Platform

This platform utilizes patented emulsification to solubilize non-oil-soluble actives (e.g., Ergothioneine, Pro-Xylane) into clear, stable oil phases, ideal for advanced cosmetic formulations.

Flagship Product—— Oil Soluble Pro-Xylane

Product Features

Alcohol-free, using safe excipients, gentle skin care

Transparent and refreshing oily products.

It can be widely applied in cosmetics and essential oils to solve the dissolution problem of water-soluble components in oil-soluble systems.

Oil-soluble nanoparticles can better combine with the skin and enhance the transdermal rate of active ingredients (supported by in vitro transdermal data).

High skin permeability

In an in vitro transdermal experiment, the abdominal skin of isolated Bama miniature pigs, which is closest to human skin, was taken as a model to compare the in vitro percutaneous penetration characteristics of our 10% Pro-Xylane oil and a famous Pro-Xylane face cream.

The test results indicated that under the same loading dose condition, the intradermal retention amount of our 10% Pro-Xylane oil was 3.5 times that of the famous Pro-Xylane face cream. Furthermore, the difference between sample batches of our 10% Pro-Xylane oil is smaller, indicating that it has a superior transdermal absorption rate and intradermal retention effect.

Market-available Products

Oil Soluble Urolithin A

Oil Soluble L-Ergothionine

Oil Soluble Collagen

Oil Soluble GHK-Cu

Water-Soluble Technology Platform

We employ patented delivery systems like liposomes to significantly enhance the solubility and bioavailability of poorly soluble nutrients (e.g., Urolithin A, Fisetin) for supplement applications.

Flagship Product—— Water Soluble Fisetin

Key Product Features

Complete and homogeneous dispersion in aqueous solution

Uniform and stable system with zero sedimentation

Urolithin content up to 20–30%, with customizable concentrations available

Bioavailability enhanced by more than 5-fold

Market-available Products

Water Soluble Fisetin

Water Soluble Dihydromyricetin 30%

Water Soluble Berberine HCl

Water Soluble S-Equol

High-Bioavailability Softgel Platform

This technology enables the encapsulation of challenging ingredients (e.g., NMN, Urolithin A) into homogeneous, stable softgels with significantly improved bioavailability and manufacturing feasibility.

Flagship Product—— High-Bio Urolithin A Softgel

Key Product Features

Homogeneously dispersed fill material with complete water solubility.

Stable softgel system with no phase separation or content leakage.

Customizable formulations available to meet specific requirements.

Bioavailability increased by more than 5-fold compared to standard preparations.

Market-available Products

High-Bio Urolithin A Softgel

High-Bio Fisetin Softgel

High-Bio NMN Softgel

High-Bio Berberine Softgel

Frequently asked questions

Have other questions or just want to chat? Book a call and let’s figure it out together.

1. How is your water-soluble technology implemented, and what is its underlying mechanism?

Bonerge utilizes nanocrystal technology, which enhances the solubility and bioavailability of active ingredients through two primary mechanisms. First, by reducing particle size to the nanoscale (typically 200–250 nm), the technology significantly increases the total surface area of the compound, enabling a much faster dissolution rate. Second, nanocrystals exist as discrete, pure crystalline particles without requiring harsh chemical solubilizers. Their strong adhesion to biological surfaces and ability to establish a high local concentration gradient markedly improve skin permeation and cellular uptake of otherwise poorly soluble actives, resulting in superior efficacy.

2. What is the mechanism of your oil-soluble technology?

Bonerge's oil-soluble technology utilizes a self-emulsifying system. Self-emulsifying systems form fine micro/nanoemulsions upon contact with lipids, dramatically increasing the surface area of the active ingredient. This enhances its solubilization within oily phases and significantly improves penetration through biological membranes, thereby boosting bioavailability.

3. What water-soluble products do you offer?

Bonerge has developed water-soluble Urolithin A, water-soluble Fisetin, water-soluble Dihydromyricetin, and water-soluble Berberine. Our water-soluble technology platform is now well-established, enabling us to efficiently customize additional water-soluble products based on client needs.

4. What oil-soluble products do you offer?

Bonerge has developed oil-soluble Urolithin A, oil-soluble Fisetin, oil-soluble Boswellia Serrata Extract (Boswelox), oil-soluble L-Ergothioneine, oil-soluble Glutathione, oil-soluble Collagen Peptide, and more. We will continue to expand our portfolio of oil-soluble products for easy integration into various cosmetic formulations and can efficiently customize other oil-soluble ingredients according to client requirements.

5. What is the collaboration model for customizing water-soluble or oil-soluble products?

We begin by collecting and analyzing client needs, then prepare a preliminary proposal. Once confirmed, we proceed to sample preparation, testing, and stability studies. After the samples meet quality standards, we support planning for pharmacokinetic and clinical trials as needed. Please send your requirements to our email, and we will provide a detailed project plan.