About

Bonerge is an innovative manufacturer that provides comprehensive turn-key solutions within the fields of the Nutraceutical and Cosmeceutical ingredients industries.

Our core focus lies in the discovery and development of ingredients for Ageless Energy, Healthspan and Longevity.

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About

Bonerge is an innovative manufacturer that provides comprehensive turn-key solutions within the fields of the Nutraceutical and Cosmeceutical ingredients industries.

Our core focus lies in the discovery and development of ingredients for Ageless Energy, Healthspan and Longevity.

Contact
About

Bonerge is an innovative manufacturer that provides comprehensive turn-key solutions within the fields of the Nutraceutical and Cosmeceutical ingredients industries.

Our core focus lies in the discovery and development of ingredients for Ageless Energy, Healthspan and Longevity.

Contact
Bonerge

Oil Soluble Pro-Xylane

Utilizing patented emulsification technology, this oil-based Pro-Xylane solution offers a clean, transparent, and stable matrix with a content exceeding 10%, ideal for advanced skincare formulations.

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Bonerge

Water Soluble Fisetin

Fully soluble in water, this clear and transparent Fisetin solution contains 5%–10% active ingredient with customizable concentration options for versatile product applications.

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Bonerge

Urolithin A High-Bioavailability Softgel

Featuring a uniform and easily dispersible core matrix, this softgel formulation enhances the bioavailability of Urolithin A by 5 times, offering optimized efficacy and user experience.

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Fisetin Benefits for Ovarian Health: Supporting POI, PCOS and Menopause

Fisetin Benefits for Ovarian Health: Supporting POI, PCOS and Menopause

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Fisetin Benefits for Ovarian Health: Supporting POI, PCOS and Menopause

Fisetin Benefits for Ovarian Health: Supporting POI, PCOS and Menopause

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Fisetin Benefits for Ovarian Health: Supporting POI, PCOS and Menopause

Fisetin Benefits for Ovarian Health: Supporting POI, PCOS and Menopause

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At Bonerge, we believe that meaningful progress is born from collaboration. We are committed to building open, trusting, and long-term partnerships that drive innovation and create shared value.

At Bonerge, we believe that meaningful progress is born from collaboration. We are committed to building open, trusting, and long-term partnerships that drive innovation and create shared value.

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At Bonerge, we believe that meaningful progress is born from collaboration. We are committed to building open, trusting, and long-term partnerships that drive innovation and create shared value.

At Bonerge, we believe that meaningful progress is born from collaboration. We are committed to building open, trusting, and long-term partnerships that drive innovation and create shared value.

Talk to Our Team
Fuel Your Vitality with High Quality NMN
Fuel Your Vitality with High Quality NMN

Fuel Your Vitality with
High Quality NMN

What is NADHelp+® ?

NADHelp+ is your trusted brand of premium-grade NAD+ precursor ingredients, including NMN, NMNH, NAD, and NADH, offering superior quality at competitive prices through large-scale manufacturing.

What is NADHelp+® ?
Green Enzymatic Process

Green Enzymatic Process

Large-scale commercial production utilizing a green enzymatic process, ensuring competitive product pricing.

Stringent Quality Control Standards

Stringent Quality Control Standards

Produced under GMP and HACCP systems, ensuring batch-to-batch purity >99.9%.

Excellent Flowability

Excellent Flowability

Offered in bulk densities of 0.4–0.8 g/ml with superior flowability. Custom densities available.

Superior Stability

Superior Stability

Stable at room temperature with no yellowing or moisture absorption. Shelf life: 2 years under proper storage.

About NMN
Benefits
Clinical Summary
Application
Why Choose
Quality Assurance
FAQs
Recommend Products
About NMN

About NMN

NMN (β-Nicotinamide Mononucleotide) is a naturally occurring nucleotide found in a variety of foods, with avocados, broccoli, and edamame among the richest dietary sources. As a key NAD⁺ precursor, NMN plays a pivotal role in cellular energy metabolism and age-related physiological functions.

As a rising star in the longevity field, NMN is regarded as a“next-generation anti-aging molecule.” On September 29, 2025, the FDA officially confirmed NMN as a legal dietary supplement, opening new opportunities for its application in food and supplements.

About NMN

Health Benefits

Enhances Cellular Energy Production

Enhances Cellular Energy Production

As a direct precursor to NAD+, NMN effectively replenishes cellular NAD+ levels, thereby optimizing mitochondrial function and boosting ATP generation. This leads to improved cellular vitality and overall energy metabolism.

Geroscience. 2023 Feb;45(1):29-43.

Supports Healthy Aging & Longevity Pathways

Supports Healthy Aging & Longevity Pathways

NMN activates key longevity proteins such as sirtuins (particularly SIRT1 and SIRT3), which play crucial roles in DNA repair, gene expression regulation, and cellular stress resistance. This helps slow down cellular aging processes.

Mol Biol Rep. 2022 Oct;49(10):9737-9748.

Promotes Metabolic & Cardiovascular Health

Promotes Metabolic & Cardiovascular Health

Research indicates that NMN supports healthy blood sugar metabolism, improves insulin sensitivity, and enhances vascular function by maintaining endothelial health and promoting healthy blood flow.

Int J Mol Sci. 2024 Sep 2;25(17):9526.

Supports Cognitive & Neurological Function

Supports Cognitive & Neurological Function

By increasing NAD+ levels in the brain, NMN helps protect neurons from oxidative stress, supports mitochondrial health in neural cells, and may enhance memory, learning ability, and overall neurological resilience.

Cancer Res. 2021 Jul 1;81(13):3727-3737.

Enhances Cellular Energy Production

As a direct precursor to NAD+, NMN effectively replenishes cellular NAD+ levels, thereby optimizing mitochondrial function and boosting ATP generation. This leads to improved cellular vitality and overall energy metabolism.

Geroscience. 2023 Feb;45(1):29-43.

Supports Healthy Aging & Longevity Pathways

NMN activates key longevity proteins such as sirtuins (particularly SIRT1 and SIRT3), which play crucial roles in DNA repair, gene expression regulation, and cellular stress resistance. This helps slow down cellular aging processes.

Mol Biol Rep. 2022 Oct;49(10):9737-9748.

Promotes Metabolic & Cardiovascular Health

Research indicates that NMN supports healthy blood sugar metabolism, improves insulin sensitivity, and enhances vascular function by maintaining endothelial health and promoting healthy blood flow.

Int J Mol Sci. 2024 Sep 2;25(17):9526.

Supports Cognitive & Neurological Function

By increasing NAD+ levels in the brain, NMN helps protect neurons from oxidative stress, supports mitochondrial health in neural cells, and may enhance memory, learning ability, and overall neurological resilience.

Cancer Res. 2021 Jul 1;81(13):3727-3737.

Clinical Summary

Blood NAD Levels

Muscle Insulin Sensitivity

Aerobic Capacity

 Blood NAD Levels

Ingestion of NMN increased blood NAD levels, maintained walking speed, and improved sleep quality in older adults

Enrolled: 60 healthy adults aged 65-75 years

Dosage: 250 mg/day NMN

Control Group: Placebo

Trial Cycle: 12 Weeks

Detection Indicators: Motor function test, Physiological tests, Blood and urine analysis, Analysis of blood NAD related metabolites, Questionnaire, Safety assessment

Result: NMN intake could increase blood NAD + levels, maintain walking speed, and improve sleep quality in older adults. Interventions involving NMN aimed at maintaining walking speed could contribute to extended healthy life expectancy.

ID: JPRN-UMIN000047871; DOI: 10.1007/s11357-024-01204-1

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 Muscle Insulin Sensitivity

NMN increases muscle insulin sensitivity in prediabetic women

Enrolled: 25 women with prediabetes (body mass index 25.3 to 39.1 kg/m2)

Dosage: 250 mg/day NMN

Control Group: Placebo

Trial Cycle: 10 Weeks

Detection Indicators: Body composition, Skeletal muscle insulin sensitivity and signaling, Muscle NAD+ content and global gene expression profile

Result: Insulin-stimulated glucose disposal, skeletal muscle insulin signaling and the expression of platelet-derived growth factor receptor β and other genes related to muscle remodeling increased after NMN supplementation in women with prediabetes who are overweight or obese.

ID: NCT03151239; DOI: 10.1126/science.abe9985

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Aerobic Capacity

NMN supplementation enhances aerobic capacity in amateur runners

Enrolled: 48 healthy recreationally trained runners aged 27–50 years

Dosage: 300, 600 and 1200 mg/day NMN + Training

Control Group: Placebo + Training

Trial Cycle: 6 Weeks

Detection Indicators: Anthropometric data, Cardiopulmonary endurance performance, Data collection and reduction

Result: Oxygen uptake (VO2), VO2max, power at first and second ventilatory threshold were increased in NMN groups (600 and 1200 mg/day). It showed that NMN increased the aerobic capacity of humans during exercise training, and the improvement was likely the result of enhanced O2 utilization of the skeletal muscle.

ID: ChiCTR200003513; DOI: 10.1186/S12970-021-00442-4

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Available in

Tablets

Tablets

Hard Capsule

Hard Capsule

Soft Capsule

Soft Capsule

Powders

Powders

Beverages

Beverages

Gummies

Gummies

Liquids

Liquids

Recommended Formulation

Resveratrol
Fisetin
PQQ
Resveratrol
Resveratrol

Resveratrol

Resveratrol amplifies NMN's effect by activating sirtuins, especially SIRT1, for which NAD+ (boosted by NMN) is an essential cofactor, creating a powerful synergy for cellular defense and gene regulation.

Fisetin
Fisetin

Fisetin

Fisetin's senolytic action clears aged, NAD+-consuming cells, while NMN replenishes NAD+ levels in healthy remaining cells, jointly promoting a more efficient and youthful tissue environment.

PQQ
PQQ

PQQ

NMN replenishes NAD+ to fuel mitochondrial function, while PQQ directly stimulates the biogenesis of new mitochondria, resulting in a powerful synergy that comprehensively enhances cellular energy production and vitality.

Quality Assurance

NON-GMO

NON-GMO

ISO 9001

ISO 9001

Gluten Free

Gluten Free

BSE Free

BSE Free

Halal Certified

Halal Certified

Kosher Certified

Kosher Certified

HACCP

HACCP

ISO 22000

ISO 22000

Frequently Asked Questions

Frequently Asked Questions

What are the advantages of your NMN?

Our NMN is produced in a GMP-certified facility using enzymatic process at a large commercial scale, with a monthly capacity of 30 metric tons, ensuring both high quality and excellent cost-effectiveness.

What bulk density specifications does NADHelp+ NMN offer?

We offer standard bulk densities of 0.4 g/ml and 0.6 g/ml. Custom density specifications are also available upon request to meet specific client needs.

Do you maintain NMN inventory in the United States?

Yes, we keep regular inventory in Los Angeles, USA, which enables fast order fulfillment and responsive service.

What is the recommended dosage of NMN?

The typical daily dosage for standalone NMN supplementation is 500 mg.

What is the minimum order quantity (MOQ) for your NMN?

Our NMN is packaged in 25 kg drums, so the minimum order quantity is 25 kg.
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