Supplementation with urolithin A can increase NAD+ levels in the body with mice experiencing an approximate 50% elevation in NAD+ levels. UA supplementation was comparable to the effect obtained by supplementing nicotinamide riboside, precursor of NAD, at a five-fold higher dose. Moreover, Urolithin A can increase NAD levels while reducing uric acid levels.

Journal of photochemistry and photobiology. B, Biology, 232, 112462.

Urolithin A can affect the expression rhythm of clock genes in intestinal epithelial cells, including expression level, amplitude, and peak phase. This regulation controls the timing of various physiological activities, ensuring that processes such as sleep, digestion and metabolism are aligned with the circadian cycle.

Nutrients, 16(14), 2263.

On the one hand, UA can reduce 45% melanin production in melanoma cells by inhibiting tyrosinase activity, and the effect is equivalent to that of 5μM kojic acid (positive control).

On the other hand, UA can also promote the blood vessels rapidly formed within the wound, and the deposition and remodeling of collagen matrix were accelerated. UA group's wounds exhibited the significantly higher intensity of collagen I and III deposition than control, and by day 21, the UA group's wounds were almost completely closed.

Journal of agricultural and food chemistry, 65(32), 6870–6876. / Frontiers in pharmacology, 13, 806284.

AS a postbiotics, UA can effectively restrain the proliferation of Helicobacter pylori (Hp) and its adhesion to cells, thereby diminishing gastrointestinal damage caused by Hp. 

And UA can promotes the expression of MUC2 protein, enhancing the thickness of the colonic mucus layer, reducing mucosal permeability and consequently strengthening intestinal barrier function.

Journal of agricultural and food chemistry, 70(38), 11981–11993. /  Scientific reports, 14(1), 15706.

· Urolithin A ingredients on the market exhibit diverse colors, such as gray, light brown, off-white, and yellow. For high-purity products, color directly reflects product purity and impurity levels.  

· Powder Hue: StanYouth stands out with its immaculate and pale yellow shade.

· Solution Hue: Upon dissolution of urolithin A within organic solvents, latent impurities that are not perceptible in the solid state may become manifested. 

· Since there is currently no official high-quality reference standard available, we have to resort to multiple characterization methods such as HPLC and HNMR for the purity testing of urolithin A to ensure that its purity complies with the specifications.

· The purity of StanYouth Urolithin A, as determined by HPLC and HNMR, is greater than 98%. Moreover, We calibrated the in-house reference substance and used it for content examination to ensure the consistency of each batch.