
AM06® Akkermansia muciniphila
Intestinal Health Companion
· Akkermansia muciniphila (AKK) is a natural occuring bacteria found in the intestinal microbiome, making up 1%-5% of the microbiome in healthy people.
· AM06 AKK, the exclusive probiotic strain derived from human breast milk, holds SA-GRAS Certification and boasts a robust IP portfolio with 6 granted patents and 22 pending applications.

Product Brief
Accumulating evidence shows Akkermansia helps maintaining the integrity of the intestinal barrier, fine-tuning the host's immune response, and enhancing multiple metabolic pathways. Compared to traditional probiotics, AKK stand out as the most promising next-generation probiotic and one of the first microbes for clinical use.
Scientific Research of Akkermansia muciniphila:
· Lower AKK Levels Link to Poor Health
· Help for Weight Management
· Support Metabolism Health
Scientific Researches

Lower AKK Levels Link to Poor Health
Scientific research has uncovered that AKK plays a beneficial role in preventing gut barrier damage and reducing insulin resistance. When the amount of AKK in the gut is insufficient or has decreased, it has been associated with the occurrence of various metabolic disorder. When AKK is present in the gut, it contributes to a stronger gut lining. Moreover, it has been proven to have a positive effect on improving metabolic disorders and assisting in maintaining a healthy body weight.
American journal of physiology. Endocrinology and metabolism, 317(3), E446–E459.

Help for Weight Management
Research found that AKK can stimulate the secretion of glucagon-like peptide-1 (GLP-1). In humans, GLP-1 plays the role of helping us feel full and may aid in weight management.
In a randomized controlled trial, 32 obese or overweight people with insulin resistance took 10 billion CFU of AKK daily. After 3 months, the AKK group lost 5 Ibs more than the placebo group. On average, those taking AKK shed 3 lbs of fat and about 1 inch from their hip circumference.
Nature medicine, 25(7), 1096–1103.

Support Metabolism Health
In the models of diet-induced obesity (DIO), administration of pasteurized AKK decreased body weight and hip circumference, improved insulin sensitivity, and reduced the markers of liver damage.
Another study shows that supplementation with AKK can inhibit the activation of CCR2+ monocytes, preventing B1a cells from transforming into 4BL cells. As a result, it can reverse insulin resistance and improve a series of metabolic problems.
Frontiers in immunology, 13, 934695.
Why Choose
AM06

The Only Source of Breast Milk
· The technical development team comprehensively evaluated the general characteristics, genetic characteristics, tolerance and toxicity of 31 healthy AKK strains, and found that AM06 strain isolated from breast milk has the advantages of low toxicity, high genetic stability, high pH and bile salt tolerance, and can be used as probiotics in food.

High-Quality Patented Microbial Strain
· AM06 AKK strain has strong intellectual property protection, of which 6 patents have been granted and 22 applications have been submitted. The product adopts exclusive inactivation technology, which ensures excellent stability and effectively maintains the best biological activity of functional components. Through the strict audit of SA-GRAS certification, its safety quality is fully verified.
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Disclaimer *
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. All information is provided solely for business-to-business customers with the aim of imparting general knowledge and is not intended for end-use consumers.