NADHelp+ Precursor
NMN / NMNH / NADH
· The popular NAD+ precursors include β-Nicotinamide Mononucleotide (NMN), Reduced NMN (NMNH), Nicotinamide Adenine Dinucleotide (NADH).
· NAD+ precursors can increase the intracellular NAD+ level through biotransformation, which plays a vital role in cell metabolism and energy production.
Product Brief
NAD+ precursor supplements can participate in NAD+ biosynthesis through different biotransformation pathways. Studies have shown that in addition to maintaining cell energy homeostasis and regulating metabolic function, NAD+ precursors may also help to promote DNA health and delay the aging process of the body.
Scientific Research of NAD+ :
· Cell Energy Support
· Sirtuins Pathway Activation
· Promote DNA Health
Scientific Researches
Delay the Aging Process
Researches showed that NAD+ reduction leads to reduced SIRT1 activity, increasing proliferator-activated receptor gamma coactivator 1-alpha (PGC)-1α acetylation and decreasing transcriptional factor A mitochondria (TFAM) levels. This decline in NAD+ levels can lead to cellular dysfunction and DNA damage and aggravate age-related problems.
Molecular metabolism, 49, 101195.
Sirtuins Pathway Activation & Lipid Metabolism Regulation
SIRT1 is a NAD+-dependent protein deacetylase that plays a pivotal role in regulating cellular metabolism through lysine residue deacetylation on both histone and non-histone proteins. Evidence showed that SIRT1 functions as a key downstream mediator of NAMPT-mediated NAD+ biosynthesis in many biological processes, including oxidative metabolism enhancement and protection against high fat diet-induced metabolic abnormalities.
BioEssays, 39(5), 10.1002/bies.201600227.
Promote DNA Health & Cognitive Function
DNA polymerase β (Polβ) is the key protein of DNA base excision, which is closely related to DNA repair activity. NAD+ supplementation with nicotinamide riboside significantly normalized neuroinflammation, synaptic transmission, phosphorylated Tau, and DNA damage as well as improved learning and memory and motor function of DNA repair deficiency (3xTgAD/Polβ+/−) mice.
Proceedings of the National Academy of Sciences of the United States of America, 115(8), E1876–E1885.
Why Choose
NADHelp+ Precursor
NADHelp+ NMN / NMNH / NADH
Our NMN factory is cGMP - certified, featuring a comprehensive quality management system. Ensures both the accurate NMN content and its stability, maintaining biological activity over time.
Disclaimer *
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. All information is provided solely for business-to-business customers with the aim of imparting general knowledge and is not intended for end-use consumers.
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