图片名称

MitoSober® PQQ

Pyrroloquinoline Quinone with FDA GRAS


· PQQ (pyrroloquinoline quinone)is a natural-occurring compound that exists in soil and a variety of foods, including spinach, kiwi, soybeans, and human breastmilk.

· MitoSober® PQQ features patented crystalline technology with enhanced density, superior solubility, and FDA GRAS-certified safety, ensuring optimal bioavailability and stability.

MitoSober® PQQ
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  • MitoSober® PQQ

Product Brief

PQQ affects essential biological processes, influencing mitochondria biogenesis, reproduction, growth and aging. The absence of PQQ in diets produces a response like a vitamin-related deficiency and the current research suggest vitamin-like PQQ has strong potential as a potent therapeutic nutraceutical.

 

Scientific Research of Pyrroloquinoline quinone:

· Optimize Mitochondria Health

· Notable BBB Permeability and Neuroprotective Activity

· Support Skeletal Muscle Health

 

Scientific Researches

Optimize Mitochondria Health

Optimize Mitochondria Health

PQQ optimizes mitochondrial function, aids new mitochondria development, and boosts cellular energy production. In college-age humans, 5-10 mg daily PQQ supplementation improves lactate-to-pyruvate ratio and urinary metabolites, showing enhanced mitochondrial oxidation. Also, 20 mg daily PQQ optimizes mitochondrial biogenesis.

 

The Journal of nutritional biochemistry, 24(12), 2076–2084.

Notable BBB Permeability and Neuroprotective Activity

Notable BBB Permeability and Neuroprotective Activity

PQQ has high blood-brain barrier (BBB) permeability and low toxicity. In Aβ1-42-induced AD mouse models, in-vivo tests prove PQQ can reduce cognitive deficits.

 

PQQ regulates genes crucial for synapses and reduces neuronal damage, cuts down reactive oxygen species production, and affects the SIRT1 and CREB pathways,revealing the key molecular mechanisms of its neuroprotective effects.

 

Advanced science (Weinheim, Baden-Wurttemberg, Germany), 11(18), e2308970.

Support Skeletal Muscle Health

Support Skeletal Muscle Health

According to research, PQQ remarkably reverses the muscle mass loss and the reduction in the cross-sectional area of tibialis anterior myofibers induced by denervation. 

 

Moreover, PQQ mitigates skeletal muscle atrophy, mitophagy, and fiber type transition by inhibiting the TGF-β1/Smad3, JNK/p38 MAPK, and NF-κB signaling pathways.

 

Annals of translational medicine, 7(18), 440.

Why Choose

MitoSober

New Crystal Form with High Density and Excellent Solubility

New Crystal Form with High Density and Excellent Solubility

· The novel crystalline form of MitoSober PQQ demonstrates superior chemical and physical stability, exhibiting significant advantages in multiple technical parameters including solubility, crystalline stability, hygroscopicity, and process adaptability (filtration, drying, and tableting). This optimized crystalline structure ensures enhanced product performance and manufacturing efficiency.

Affirmed FDA GRAS & High Purity

Affirmed FDA GRAS & High Purity

· Safety and purity form the cornerstone for a product to deliver health benefits. MitoSober PQQ has not only obtained rigorous FDA GRAS certification, fully validating its safety for consumption, but also achieves an exceptional purity level of over 99% through advanced purification processes. Its superior quality standards provide reliable assurance for product efficacy, making it the preferred choice for quality-conscious consumers in the PQQ supplement market.

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Disclaimer *

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. All information is provided solely for business-to-business customers with the aim of imparting general knowledge and is not intended for end-use consumers.